Pain


Overview 

The Significance of Pain

Pain Perception

Theories of Pain

            Gate control theory

            Neuromatrix theory

Neurochemical Basis of Pain and Pain Inhibition

Acute versus Chronic Pain

Psychosocial Factors and Pain

            Gender differences

            Cultural differences

The Measurement of Pain

            Psychophysiologcial measures

            Behavioural assessment

            Self-reports of pain

            Assessing Pain in infants and children

            Assessing Pain in older adults

Pain Control Techniques

            Pharmacological control of pain

            Surgical control of pain

            Transcutaneous electrical nerve stimulation

            Accupuncture

            Physical Therapy

            Massage

            Relaxation

            Distraction

            Biofeedback

            Hypnosis

            Multidisciplinary pain management programmes

 


 

 

The Significance of Pain

    Pain has an evolutionary value, it keeps us avoiding danger and 1) stops us before serious injury happens, 2) prevent further injury, through learning, and 3) provides a brake on activity to ensure healing and recovery.

 

Pain Perception

Various theories of pain are present, each building from the basic physiology of pain. 

Afferent sensory nerves carry signals from nociceptors, pain receptors.
 

Two types of fibers are present, A-delta- fibres ( small, myelinated, fast) and C-fibres (large slow, non-mylenated).  The relative balance of activation of these fibres gives rise to pain or not.

 

Theories o f Pain

          Pain  

Gate Control Theory of Pain Signals passing through the spinal chord "gate" to brain lead to experience of pain. Some neurons open and some close the (inhibitory) gate.

Three Components
to the Gate
A-delta fibres
  Two fibres and one interneuron
C-fibres
Slow- small  Inhibitory Fast  large fibre pressure 
dull or chronic pain  Inter-
Neuron
"emergency" signals
-fast "closing' fibres can be stimulated by massage to stop the fast searing pain by activating the inhibitory inter-neuron.

-also have descending cortical nerves to close gate

-slow (small) fibers inhibit the inhibitory inter-neuron and activate the projection (pain) neuron, opening the gate and giving PAIN

Phantom Pain - aching, burning or sharp pain in a limb or organ that had been amputated. Why?  See video from you tube of VS Ramachandran @ 3:30 (prt2)

Two possibilities:
1) Impulses that had previously closed the gate are reduced or lost
2) Once pain producing activity begins in the brain it continues without sensory input (being stimulated by neighbouring brain areas-i.e., face-hand)
3) Other brain parts are "calling" the missing limb.

Anomalies: People born with missing limbs have never had normal sensory experiences why do they experience phantom fingers or toes?
 


 

Neurochemical Basis of Pain and Pain Inhibition- midbrain area - periaqueductal gray electrical stimulation leads to a blocking of pain.  This is an example of a stimulation-producted analgesia.

 

Endogeous opioids - natural brain chemicals that regulate pain. Found in the brain, spinal chord and glands, they act on brain sites that are also acted upon by heroin, opium &  morphine.

 

Acute versus Chronic Pain  acute-short term, chronic-ongoing are seen in various forms such as chronic recurring, chronic intractable benign, responded, operant pain and pain behaviours.

 

 

Psychosocial Factors and Pain

            Gender differences  - some suggestions that women have lower pain threshold and levels of pain tolerance.  Others studies refute these claims suggesting that men tend to report less pain due to social expectations.

 

            Cultural differences -  meaning of events and expectations of pain vary.

 

The Measurement of Pain - difficult to measure, almost no overt behaviour for it. 

            Psychophysiologcial measures : EMG, autonomic activity, electronencephalography, evoked potentials.

            Behavioural assessment : non-verbal facial and vocal cues, postural form, movement, supplemental spousal diaries and estimates of pain.

           

Self-reports of pain : interviews, rating scales (visual analog scale, box scale, verbal rating scale) <see Figure 10-1> Pain questionnaires also are useful, such as the McGill Pain Questionnaire (MPQ) or the West Haven-Yale Multidimensional Pain Inventory (MPI).

 

            Assessing Pain in infants and children - is often very difficult

            Assessing Pain in older adults - also has limitations

 

 

Pain Control Techniques

            Pharmacological control of pain
Peripherally acting analgesics - non-narcotic analgesics act on entire body (ASA, Ibuprofin).

Centrally acting analgesics - narcotics opium, morphine, codeine as well as Percodan & Demerol.

Local anesthetics - acting topically or through injection,  i.e., novocaine.

sedatives & tranquilizers - not really blocking pain, but relaxing and enhancing the effect of others through additive effects.

 

            Surgical control of pain  - severing the nerves to spinal chord or to brain. Not always working well, (see phantom pain).

            Transcutaneous electrical nerve stimulation - electrodes placed on skin (non-invasive).

            Acupuncture - balance and flow of qi through the body, to ameliorate the pain.
 

            Physical Therapy

            Massage - various types (Swedish, Shiatsu, Tai Chi.

            Relaxation - progressive muscle relaxation, guided imagery <the Matrix>

            Distraction - changing focus of attention and reinterpreting what is there.

            Biofeedback - electrico-mechanical information feedback about the state of the body.

            Hypnosis - effective in cutting reports and over behaviour of pain (cold presser) but also showing subtle signs of pain, through ANS as well as hidden observer.

            Virtual Reality

            Multidisciplinary pain management programmes - bringing together the talents of professionals from a host of areas to provide a broad and comprehensive program. Such points of concern are: perception of pain, improving physical lifestyle, social support, reliance upon medication, use of healthcare facilities.